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BuSpar General Information

Anxiety disorders, which belong to the psychological problems, include a number of conditions, such as Generalized Anxiety Disorder, Panic Disorder, Agoraphobia, Obsessive-Compulsive Disorder, Post-traumatic Stress Disorder, Social and Specific Phobias.

Doctor’s prescription and a drug store crammed with medications against all the possible known to people diseases can be a means of solving the problem for those who suffer from anxiety disorders. BuSpar pills are believed to be effective treatment option against them.

What Is BuSpar Prescribed for?

BuSpar is a medication used for relieving mild to moderate symptoms associated with Generalized Anxiety, such as nervousness, irritability, dizziness, and tension. However, it should be noted that this drug has shown little effectiveness in the treatment of severe anxiety, Panic Disorder, and Obsessive-Compulsive Disorder. On the other side, it can be used for managing premenstrual syndrome symptoms.

Drugs Class and Action

BuSpar is an anti-anxiety medication with the active ingredient buspirone, which is also available in a generic form. The drug belongs neither to benzodiazepines, barbiturates, nor other sedative/anxiolytic medicines. It has no sedative or anticonvulsant effects on the body.

The exact mechanism of the pills action is unknown; scientists state that they affect serotonin (5-HT1A) and D2-dopamine receptors and may have influence on the other neurotransmitter systems, changing the messages that nerves transmit to each other.

Side Effects

Adverse reactions belong to a very important aspect of the treatment with pharmaceutical drugs. Patients should be aware of the undesirable feelings, which can be caused by BuSpar. Among the most frequent side effects are headache, nausea, dizziness, and drowsiness. Nervousness, lightheadedness, excitement, fatigue, and insomnia also tend to appear in quite a large number of users.

There are also side effects, which occur seldom; still, patients should be informed about them: rash, sweating, muscle aches, rapid heartbeat or palpitations, difficulty concentrating and some others.

BuSpar Dosage

The usual starting dose of the pill is 15 mg, divided into three equal portions and taken three times a day with or without food. To make the dividing of the tablet easier there exist a special Buspar Dividose with marks indicating where to break the pill.

Every two or three days a doctor may increase the dose. The first improvements of the symptoms may be observed in 7-10 days of treatment, but the maximum effect the medication will have in about 4 weeks. The use of BuSpar for a longer period of time is not recommended, although there is no data reporting about any danger or risk if the drug is taken longer.

Drug Interactions

The most dangerous interaction of BuSpar is with MAO inhibitors (rarely used for the treatment of depression, agoraphobia, psychotic disorders, etc.), and blood thinners (warfarin).

BuSpar may also interact with antibiotics and antifungal medicines, cardiovascular drugs and anticonvulsants, narcotic pain medicines and sleeping pills. Be sure to tell a doctor about any drugs you are currently taking.

This medication should not be taken with grapefruit juice or alcohol.

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Precautions and Contraindications

Liver or kidney disease and allergy to BuSpar components are the most prominent contraindications while considering treatment with this drug. Elderly are said to be safely and effectively treated with BuSpar similar to younger patients.

The trials conducted in pregnant and breastfeeding women revealed no dangerous fetal development abnormalities or passing into the breast milk. However, the use by such patients should be strictly monitored by doctors and the treatment should be started only if benefits will definitely overweigh the possible risks.


Although a distinct benefit of BuSpar is the absence of sedative effect, patients treated with this drug are encouraged to avoid or be especially cautious while driving or working with machinery.  


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