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Celexa vs. Lexapro

Good evening, ladies and gentlemen! Today we all will be witnesses of the extraordinary duel, which is really unique for the whole history of boxing. Today we see Celexa in the red corner and Lexapro in the blue corner… Oh, do not try to find the names of these boxers in the lists of the most popular fighters. In fact, these names can be easier found in any pill book or pharmaceutical annals. That is why our today evening is unique – yes, for the first time we have medications on the ring, and not real boxers. The goal of our today fighters is not to beat the opponent and get the champion belt, but to demonstrate as much effectiveness and safety as possible in treating depression and anxiety disorders.

Well, in accordance with the laws of the genre, first of all, we have to present the general profile of both participants of the duel. So, both Celexa and Lexapro are the representatives of the most up-to-date group of medications, known as SSRI or selective serotonin reuptake inhibitors. They are both promoted by one and the same company – Forest Pharmaceuticals, Inc. And though Lexapro represents the younger generation of SSRIs, being, in fact, the successor of Celexa – both medications are indicated for treating depression and general anxiety disorders in humans.

Traditionally, before coming out to the ring, all the boxers undergo weighing procedure. So, following are the results of weighing our participants: the most amazing result is that both Celexa and Lexapro can have several different weights or doses (this fact is, definitely, extraordinary for traditional boxing). Celexa can be either 10 mg, 20mg or 40mg, while Lexapro can be either 5 mg, 10 mg or 20 mg.

Finally, it is show time for boxing…

Round 1. Key Ingredients

As we have already mentioned, Lexapro is the successor of Celexa. It is because it contains the “improved” version of the key working ingredient, used in Celexa. While citalopram hydrobromide is the “heart” of Celexa, escitalopram oxalate is what makes Lexapro work. In fact, Lexapro was designed using the most up-to-date technology, known as single isomer isolation, which allowed magnifying the effectiveness and safety of the working agent, used in Celexa for many years. Using its brand-new technology Lexapro seems to have more chances to win the first round of our virtual duel.

Round 2. Principle of Action

Being the representatives of the same group of medications, Celexa and Lexapro use similar methods to beat their mutual opponents: depression, anxiety or both. These medications work in human brains by preventing the reabsorption of serotonin, which is one of the neurotransmitters (chemicals, delivering signals from one brain cell to another). As the result, the amount of serotonin increases, and this is believed to have positive effect on relieving the symptoms of depression or anxiety. Taking into account the similar methods of fighting used by Celexa and Lexapro – the second round ended in a draw.

Round 3. Effectiveness

At the very beginning of this round it becomes obvious that Lexapro prevails over Celexa in its effectiveness. Mainly, it is because Lexapro may ensure the same antidepressant effect with the lower dose than Celexa. Looks like Lexapro strikes with less power but more precisely.

Well, there are only a few seconds left to the end of this round, but it is still unclear whether the victory should be awarded to Lexapro or to Celexa. While the majority of referees decided to give Lexapro higher rates, there are still many experts saying that different patients respond differently to the medications, and it is not rare for Celexa to show better results in comparison with Lexapro. Meanwhile, Lexapro demonstrates one more benefit, starting to work much quicker against depression, and… this final argument becomes crucial - Lexapro ends this round as the winner.

Round 4. Safety

Evaluating safety profiles of Celexa and Lexapro is not an easy task; however, it is far more difficult to define the safer medication among these two antidepressants. The most common side effects are nausea, insomnia, problems with ejaculation, drowsiness and fatigue. The same adverse reactions have been identified in association with both Celexa and Lexapro. However, some statistic data says that people on Lexapro have approximately the same chances to experience side effects as people, taking sugar pills. On the other hand, Celexa may sometimes cause tremor, dry mouth and diarrhea, - reactions, that are not typical for Lexapro. So, Lexapro seems to be more convincing during this round too.

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Referee Verdict

The referee on the ring decided to end up the duel between Celexa and Lexapro. While both medications demonstrated high potency in fighting depression symptoms, the referee on the ring decided to award victory to Lexapro, which seemed to be quicker, safer and more precise during the duel.

After all, the final verdict remains after the professional doctor or health-care provider, who will assess all the advantages and disadvantages of both competitors and announce a final verdict. However, do not be surprised if the verdict varies in every particular case.


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