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Paxil Use against Premenstrual Dysphoric Disorder

They say that every woman suffers the result of the sin committed by the first woman on Earth Eve being doomed to give birth to her kids in pain and to cope with monthly menstruation and everything that comes with it, namely physical pain, fatigue, and exhaustion, as well as emotional irritation, strain, and anxiety.

Meanwhile, it goes without saying that people surrounding a woman with the symptoms of her periods also suffer the consequences, having no other way out than to bear it all, have patience, and even support the beloved person realizing her sufferings.

Premenstrual Dysphoric Disorder Facts

Definitely, women with premenstrual syndrome (PMS) symptoms deserve understanding and comforting. By the way, about 75% of all women experience these conditions. However, 3% to 8% of them have to undergo medicinal treatment besides family support, counseling groups, psychological help, and even nutritional changes. The matter is that they have to overwhelm the severe symptoms of far more serious premenstrual dysphoric disorder (PMDD), which affects women of childbearing age.

Its signs generally resemble those of PMS; however, they are always severer. Women feel so much depressed, hopeless, anxious, irritable and angry. They are prone to sudden mood swings, conflicts with other people (even or especially with those they love), insomnia and appetite changes. In fact, they lose control, interest in everyday activities and life in general. It is difficult for them to concentrate. Physical pain, breast tenderness, bloating, headaches, muscle and joint aches crown their misfortunes and make it still more difficult to live over the period of the symptoms outburst.

PMDD signs come in the second half of the cycle, subside with menstruation beginning, and vanish shortly thereafter. They are usually so severe that interfere with everyday activities and disrupt the usual life rhythm of a woman. That is, actually, the difference between PMS and PMDD.

A number of factors, as genetic predisposition, psychological, social, and cultural conditions, may be the possible triggers of the disease.

It is suggested that the imbalance in the serotonin levels (a chemical neurotransmitter in the brains) caused by ovarian function may be the reason for PMDD development. This theory is supported by the majority of scientists, since it is known that antidepressants, which affect serotonin (increasing its level) work effectively for the disorder symptoms lessening.

Paxil Therapy

One of the three selective serotonin reuptake inhibitors (SSRIs) prescribed for the treatment of premenstrual dysphoric disorder is Paxil. The pill’s working ingredient is paroxetine hydrochloride. It is used if depression and symptoms related to it are the most pronounced during the disease outbreak.

Paxil can be taken continuously if PMDD symptoms are severe, or only during the disease onset (usually two weeks prior to menstruation) if the signs are less severe.

The common side effects of Paxil therapy are sleepiness, dizziness, headaches, gastrointestinal problems, nausea, vomiting, sweating, and dry mouth. The signs of overdose are tremor, decreased urination, blurred vision, rapid heartbeat, confusion, aggression, seizures and coma.

A number of drugs can interact with Paxil; thus their combinations should be avoided. It is not recommended to take Paxil along with blood thinners, medicine against tachycardia, other antidepressants, pain killers, and many other drugs. Besides, it is dangerous to combine Paxil with alcohol and cigarettes.

People with liver and kidney diseases may not be recommended to take this SSR inhibitor. Other contraindications include pregnant and breastfeeding women, children under 18, and those allergic to Paxil ingredients. People with the history of seizures should use this drug with caution.

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It should also be noted that the symptoms of depression and mania signs may be aggravated at the beginning of the treatment. The obvious results may not be observed until the third menstrual cycle; a patient should not despair and continue the treatment as prescribed by a doctor giving some time for the medicine to start working.

Definitely, PMDD is a condition, which can destroy and destruct a woman, interfering with her family relationships, communication with friends and colleagues, and tear her life apart; however, its symptoms can be effectively lessened these days that more and more health-care providers treat this disorder seriously and become more attentive to women’s complaints, showing no disregard to them, as it used to be some time ago.


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