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Treating Depression with Pristiq

The appearance of the new drugs on the market always gives the way to the new hopes of millions of people who are eager to discover one day their health conditions may finally be treated effectively and safely. In spite of the numerous medications, available on sale today, human kind still continues to lose the battle with diseases. That is the reason why we all look for the new drugs, as well as the reason why scientists go on searching for the options more effective than older medications. Manufacturers are also interested in the work of scholars and the brightest minds of today (usually interest manifests itself in the form of income rather than health of their customers). 

Pristiq is a “brand new” medication indicated for the treatment of depression. It may also be used for the lessening of other mental illnesses symptoms as, for example, anxiety. Desvenlafaxine is the active ingredient of Pristiq, which is, actually similar to venlafaxine used in Effexor. It is a representative of serotonin-norepinephrine reuptake inhibitors (SNRIs). These drugs work in the human brain to balance the level of serotonin and norepinephrine – chemicals, which ensure the communication between brain nerve cells.

 Any message is transmitted from one cell to another with the help of these chemicals, called “neurotransmitters”. They are released from one cell into the “gap” between it and the next cell. The latter absorbs some amount of the chemicals, thus receiving the message, but some quantity of neurotransmitters is absorbed by the initial cell as well (this process is called “reuptake”). SNRI drugs are used to prevent this reuptake so that the next cell would have larger amount of neurotransmitters to absorb.
Along with increasing the level of these neurotransmitters in the space between the cells, Pristiq has some other actions in the organism, which are considered undesirable. These side effects usually subside with time. They are headaches, insomnia, dry mouth, sweating, fatigue, diarrhea or constipation, nausea and vomiting. Hypertension is also possible. One more adverse reaction refers to reproductive system of men: low sex drive, erectile dysfunction, and ejaculation abnormalities were reported.
One more note should be made about the possibility of depression aggravation at the beginning of the treatment with Pristiq; thus, doctor’s monitoring of the therapy is always a must. Any changes in the behavior (mood swifts, panic attacks, suicidal thoughts, etc.) should be immediately reported to the doctor. People younger than 24 and older than 65 are at the greater risk of this type of side effect.
The benefit of Pristiq in comparison to the older medicines is that the form of this drug allows it to be released in the body in small doses for a long period of time. It results in the decrease of dizziness and drowsiness this medicine may otherwise cause.  
Taking the drug exactly as prescribed by a doctor may significantly ease the therapy and prevent side effects occurrence. The common recommendations include not exceeding the dose, taking medicine before going to bed without chewing or crashing it, and not prolonging or reducing the treatment period. Discontinuation the drug slowly and gradually will help avoid withdrawal symptoms.
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Pristiq may interact with many medications, for example, it should not be used with other antidepressants (MAOIs, tricyclics, lithium), anti-migraine medicines, weight-loss drugs, anticoagulants and blood-thinners, cold and anti-allergic medications, narcotics, muscle relaxants, and other pills.

Pregnant and breast-feeding women, sufferers of kidney, cardiovascular, and liver disorders, people with seizures and mental illnesses history may be contraindicated against the use of Pristiq, may need dose adjustment, or require constant doctor’s monitoring.


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